Connecting you with the University of Missouri’s innovative research and creative activity

Fostering the Future of Undergraduate Research

A visit with Ted Tarkow, Professor of Classical Studies & Associate Dean of Arts & Science

By LuAnne Roth
Published: - Topics: undergraduate research pre-professional education mentorship

Altered Nuclear Gene Expression in Response to Mitochondrial Mutations in Maize


Scott Nichols, Chemistry

Kathleen Newton, Mentor

Maize non-chromosomal stripe (NCS) plants are defective plants with mutations within mitochondrial DNA (mtDNA). NCS mutants are known to synthesize several stress proteins in response to defective mitochondria. The purpose of my study was to discover which other proteins have altered expression in the mutants. Changes in RNA levels can indicate which proteins differ in expression. Using microarrays, this study compares the RNAs of the NCS2 mutant to those of a normal relative. Many differences in RNA levels were observed. Results are still being analyzed to determine how many of the apparent differences are statistically significant.