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Articles Tagged with donor

A Bacon of Hope

An interview with Randall Prather, Professor, Division of Animal Sciences

Take a good, hard mental image of a long line of people stretched for blocks. If you expand the line to roughly 100,000, this is the number of people waiting for an organ transplant. The imbalanced patient-to-organ ratio leaves many to die while waiting their turn. In response, some researchers try to tap into animal organs to save human lives, but those organs do not always work.

Research in the University of Missouri’s Division of Animal Sciences may help solve this medical debacle by using genetic modification. When an organ goes from one animal to another (like to a human), preexisting antibodies in the human bind to the organ’s sugar molecules and kill the organ, making it useless. “When you take a pig cell and transfer it to a human, the molecule is immediately recognized as foreign,” explains MU’s Animal Science Professor, Randall Prather. “Within minutes you’ll get hyperacute rejection, and the cells will be destroyed.”

Audio and Video Tagged with donor

Genetic Modification

From an interview with Randall Prather, Professor, Division of Animal Sciences

Prather talks about his work with genetic modification. The modified swine are marked by a green florescent glow on their snouts. Such modifications on the pigs could positively impact agriculture and medicine.